Cannabaceae

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Picotamide
Clinical data
AHFS/Drugs.comInternational Drug Names
ATC code
Identifiers
  • 4-methoxy-N,N'-bis(pyridin-3-ylmethyl)isophthalamide
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
ECHA InfoCard100.046.572 Edit this at Wikidata
Chemical and physical data
FormulaC21H20N4O3
Molar mass376.416 g·mol−1
3D model (JSmol)
  • O=C(NCc1cccnc1)c3cc(C(=O)NCc2cccnc2)c(OC)cc3
  • InChI=1S/C21H20N4O3/c1-28-19-7-6-17(20(26)24-13-15-4-2-8-22-11-15)10-18(19)21(27)25-14-16-5-3-9-23-12-16/h2-12H,13-14H2,1H3,(H,24,26)(H,25,27) checkY
  • Key:KYWCWBXGRWWINE-UHFFFAOYSA-N checkY
  (verify)

Picotamide is a platelet aggregation inhibitor. It works as a thromboxane synthase inhibitor and a thromboxane receptor inhibitor, the latter by modifying cellular responses to activation of the thromboxane receptor.[1] Picotamide is licensed in Italy for the treatment of clinical arterial thrombosis and peripheral artery disease.[2]

References[edit]

  1. ^ Ratti S, Quarato P, Casagrande C, Fumagalli R, Corsini A (August 1998). "Picotamide, an antithromboxane agent, inhibits the migration and proliferation of arterial myocytes". European Journal of Pharmacology. 355 (1): 77–83. doi:10.1016/S0014-2999(98)00467-1. PMID 9754941.
  2. ^ Capra V, Bäck M, Angiolillo DJ, Cattaneo M, Sakariassen KS (February 2014). "Impact of vascular thromboxane prostanoid receptor activation on hemostasis, thrombosis, oxidative stress, and inflammation". Journal of Thrombosis and Haemostasis. 12 (2): 126–137. doi:10.1111/jth.12472. PMID 24298905.

Further reading[edit]

source: Https://en.wikipedia.org/wiki/Picotamide

One thought on “Cannabaceae”

  1. Well, that’s interesting to know that Psilotum nudum are known as whisk ferns. Psilotum nudum is the commoner species of the two. While the P. flaccidum is a rare species and is found in the tropical islands. Both the species are usually epiphytic in habit and grow upon tree ferns. These species may also be terrestrial and grow in humus or in the crevices of the rocks.
    View the detailed Guide of Psilotum nudum: Detailed Study Of Psilotum Nudum (Whisk Fern), Classification, Anatomy, Reproduction

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