Cannabaceae

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Phenindione
Clinical data
AHFS/Drugs.comInternational Drug Names
Pregnancy
category
Routes of
administration		Oral
ATC code
Pharmacokinetic data
Protein binding88%
Elimination half-life5 to 10 hours
Identifiers
  • 2-phenyl-1H-indene-1,3(2H)-dione
CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.001.323 Edit this at Wikidata
Chemical and physical data
FormulaC15H10O2
Molar mass222.243 g·mol−1
3D model (JSmol)
  • O=C2c1ccccc1C(=O)C2c3ccccc3
  • InChI=1S/C15H10O2/c16-14-11-8-4-5-9-12(11)15(17)13(14)10-6-2-1-3-7-10/h1-9,13H checkY
  • Key:NFBAXHOPROOJAW-UHFFFAOYSA-N checkY
  (verify)

Phenindione is an anticoagulant which functions as a Vitamin K antagonist.

Phenindione was introduced in the early 1950s. It acts similar to warfarin, but it has been associated with hypersensitivity reactions, so it is rarely used and warfarin is preferred.[1][2]

References

[edit]
  1. ^ Naisbitt DJ, Farrell J, Chamberlain PJ, Hopkins JE, Berry NG, Pirmohamed M, Park BK (June 2005). "Characterization of the T-cell response in a patient with phenindione hypersensitivity". The Journal of Pharmacology and Experimental Therapeutics. 313 (3): 1058–65. doi:10.1124/jpet.105.083758. PMID 15743920. S2CID 17052792.
  2. ^ Sweetman SC, ed. (2009). Martindale: The Complete Drug Reference (36th ed.). London: Pharmaceutical Press. "Phenindione", p. 1369.
[edit]
source: Https://en.wikipedia.org/wiki/Phenindione

One thought on “Cannabaceae”

  1. Well, that’s interesting to know that Psilotum nudum are known as whisk ferns. Psilotum nudum is the commoner species of the two. While the P. flaccidum is a rare species and is found in the tropical islands. Both the species are usually epiphytic in habit and grow upon tree ferns. These species may also be terrestrial and grow in humus or in the crevices of the rocks.
    View the detailed Guide of Psilotum nudum: Detailed Study Of Psilotum Nudum (Whisk Fern), Classification, Anatomy, Reproduction

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