Cannabaceae

thcscience_admin
Paraoxon
Clinical data
ATC code
Legal status
Legal status
  • In general: uncontrolled
Identifiers
  • Diethyl 4-nitrophenyl phosphate
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.005.657 Edit this at Wikidata
Chemical and physical data
FormulaC10H14NO6P
Molar mass275.197 g·mol−1
3D model (JSmol)
  • [O-][N+](=O)c1ccc(OP(=O)(OCC)OCC)cc1
  • InChI=1S/C10H14NO6P/c1-3-15-18(14,16-4-2)17-10-7-5-9(6-8-10)11(12)13/h5-8H,3-4H2,1-2H3 checkY
  • Key:WYMSBXTXOHUIGT-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Paraoxon is a parasympathomimetic which acts as an cholinesterase inhibitor. It is an organophosphate oxon, and the active metabolite of the insecticide parathion. It is also used as an ophthalmological drug against glaucoma. Paraoxon is one of the most potent acetylcholinesterase-inhibiting insecticides available, around 70% as potent as the nerve agent sarin, and so is now rarely used as an insecticide due to the risk of poisoning to humans and other animals. Paraoxon has been used by scientists to study acute and chronic effects of organophosphate intoxication.[1][2] It is easily absorbed through skin, and was allegedly used as an assassination weapon by the apartheid-era South African chemical weapons program Project Coast.[3]

See also

[edit]

References

[edit]
  1. ^ Deshpande LS, Carter DS, Phillips KF, Blair RE, DeLorenzo RJ (September 2014). "Development of status epilepticus, sustained calcium elevations and neuronal injury in a rat survival model of lethal paraoxon intoxication". Neurotoxicology. 44: 17–26. doi:10.1016/j.neuro.2014.04.006. PMC 4176600. PMID 24785379.
  2. ^ Deshpande LS, Phillips K, Huang B, DeLorenzo RJ (September 2014). "Chronic behavioral and cognitive deficits in a rat survival model of paraoxon toxicity". Neurotoxicology. 44: 352–7. doi:10.1016/j.neuro.2014.08.008. PMC 4175062. PMID 25172410.
  3. ^ NTI Country Overviews:South Africa:Chemical Capabilities:Paraoxon Archived 2008-07-08 at the Wayback Machine
source: Https://en.wikipedia.org/wiki/Paraoxon

One thought on “Cannabaceae”

  1. Well, that’s interesting to know that Psilotum nudum are known as whisk ferns. Psilotum nudum is the commoner species of the two. While the P. flaccidum is a rare species and is found in the tropical islands. Both the species are usually epiphytic in habit and grow upon tree ferns. These species may also be terrestrial and grow in humus or in the crevices of the rocks.
    View the detailed Guide of Psilotum nudum: Detailed Study Of Psilotum Nudum (Whisk Fern), Classification, Anatomy, Reproduction

Leave a Reply