Cannabaceae

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ASP-7663
Names
Preferred IUPAC name
(E)-[7-Fluoro-1-(2-methylpropyl)-2-oxo-1,2-dihydro-3H-indol-3-ylidene]acetic acid
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
  • InChI=1S/C14H14FNO3/c1-8(2)7-16-13-9(4-3-5-11(13)15)10(14(16)19)6-12(17)18/h3-6,8H,7H2,1-2H3,(H,17,18)/b10-6+
    Key: RCVZUIGCNAAMIC-UXBLZVDNSA-N
  • CC(C)CN1C2=C(C=CC=C2F)/C(=C\C(=O)O)/C1=O
Properties
C14H14FNO3
Molar mass 263.268 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

ASP-7663 is a chemical compound which acts as a potent, selective activator of the TRPA1 channel. It has protective effects on cardiac tissue, and is used for research into the function of the TRPA1 receptor.[1][2]

See also

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References

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  1. ^ Pan Y, Zhao G, Cai Z, Chen F, Xu D, Huang S, et al. (2016). "Synergistic Effect of Ferulic Acid and Z-Ligustilide, Major Components of A. sinensis, on Regulating Cold-Sensing Protein TRPM8 and TPRA1 In Vitro". Evidence-Based Complementary and Alternative Medicine. 2016: 3160247. doi:10.1155/2016/3160247. PMC 4931054. PMID 27413384. S2CID 14007898.
  2. ^ Lu Y, Piplani H, McAllister SL, Hurt CM, Gross ER (December 2016). "Transient Receptor Potential Ankyrin 1 Activation within the Cardiac Myocyte Limits Ischemia-reperfusion Injury in Rodents". Anesthesiology. 125 (6): 1171–1180. doi:10.1097/ALN.0000000000001377. PMC 5110384. PMID 27748654.
source: Https://en.wikipedia.org/wiki/ASP-7663

One thought on “Cannabaceae”

  1. Well, that’s interesting to know that Psilotum nudum are known as whisk ferns. Psilotum nudum is the commoner species of the two. While the P. flaccidum is a rare species and is found in the tropical islands. Both the species are usually epiphytic in habit and grow upon tree ferns. These species may also be terrestrial and grow in humus or in the crevices of the rocks.
    View the detailed Guide of Psilotum nudum: Detailed Study Of Psilotum Nudum (Whisk Fern), Classification, Anatomy, Reproduction

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