| catenin (cadherin-associated protein), delta 1 | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | CTNND1 | ||||||
| Alt. symbols | CTNND | ||||||
| NCBI gene | 1500 | ||||||
| HGNC | 2515 | ||||||
| OMIM | 601045 | ||||||
| RefSeq | NM_001331 | ||||||
| UniProt | O60716 | ||||||
| Other data | |||||||
| Locus | Chr. 11 q12.1 | ||||||
| |||||||
| catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein) | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | CTNND2 | ||||||
| NCBI gene | 1501 | ||||||
| HGNC | 2516 | ||||||
| OMIM | 604275 | ||||||
| RefSeq | NM_001332 | ||||||
| UniProt | Q9UQB3 | ||||||
| Other data | |||||||
| Locus | Chr. 5 p15.2 | ||||||
| |||||||
δ-Catenin is a subfamily of catenin proteins with ten armadillo-repeats and includes the proteins catenin delta-1 and catenin delta-2. Catenin delta-2 is expressed in the brain where it is important for normal cognitive development.[1] Like β-catenin and γ-catenin, δ-catenins seem to interact with presenilins.[2] These catenin-presenilin interaction have implications for cadherin function and regulation of cell-to-cell adhesion.[3]
While β-catenin acts as a transcription regulatory protein in the Wnt/TCF pathway, delta-1 catenin has been implicated as a regulator of the NF-κB transcription factor.[4]
Palmitoylation of δ-catenin seems to coordinate activity-dependent changes in synaptic adhesion molecules, synapse structure, and receptor localizations that are involved in memory formation.[5]
References
[edit]- ^ Israely I, Costa RM, Xie CW, Silva AJ, Kosik KS, Liu X (September 2004). "Deletion of the neuron-specific protein delta-catenin leads to severe cognitive and synaptic dysfunction". Curr. Biol. 14 (18): 1657–63. doi:10.1016/j.cub.2004.08.065. PMID 15380068.
- ^ Rubio ME, Curcio C, Chauvet N, Brusés JL (December 2005). "Assembly of the N-cadherin complex during synapse formation involves uncoupling of p120-catenin and association with presenilin 1". Mol. Cell. Neurosci. 30 (4): 611–23. doi:10.1016/j.mcn.2005.06.005. PMID 16456928. S2CID 8841045.
- ^ Teo JL, Ma H, Nguyen C, Lam C, Kahn M (August 2005). "Specific inhibition of CBP/beta-catenin interaction rescues defects in neuronal differentiation caused by a presenilin-1 mutation". Proc. Natl. Acad. Sci. U.S.A. 102 (34): 12171–6. Bibcode:2005PNAS..10212171T. doi:10.1073/pnas.0504600102. PMC 1189325. PMID 16093313.
- ^ Perez-Moreno M, Davis MA, Wong E, Pasolli HA, Reynolds AB, Fuchs E (February 2006). "p120-catenin mediates inflammatory responses in the skin". Cell. 124 (3): 631–44. doi:10.1016/j.cell.2005.11.043. PMC 2443688. PMID 16469707.
- ^ Brigidi GS, Sun Y, Beccano-Kelly D, Pitman K, Jobasser M, Borgland SL, Milnerwood AJ, Bamji SX (January 23, 2014). "Palmitoylation of [delta]-catenin by DHHC5 mediates activity-induced synapse plasticity". Nature Neuroscience. 17 (4): 522–532. doi:10.1038/nn.3657. PMC 5025286. PMID 24562000.
See also
[edit]
Well, that’s interesting to know that Psilotum nudum are known as whisk ferns. Psilotum nudum is the commoner species of the two. While the P. flaccidum is a rare species and is found in the tropical islands. Both the species are usually epiphytic in habit and grow upon tree ferns. These species may also be terrestrial and grow in humus or in the crevices of the rocks.
View the detailed Guide of Psilotum nudum: Detailed Study Of Psilotum Nudum (Whisk Fern), Classification, Anatomy, Reproduction