![]() | |
Clinical data | |
---|---|
Other names | 7-chloro-5-(2-chlorophenyl)-N-prop-2-enoxy-3H-1,4-benzodiazepin-2-amine |
ATC code |
|
Identifiers | |
| |
CAS Number | |
PubChem CID | |
ChemSpider | |
UNII | |
KEGG | |
CompTox Dashboard (EPA) | |
Chemical and physical data | |
Formula | C18H15Cl2N3O |
Molar mass | 360.24 g·mol−1 |
3D model (JSmol) | |
| |
| |
![]() ![]() |
Uldazepam is a drug which is a benzodiazepine derivative.[1] It has sedative and anxiolytic effects similar to those of other benzodiazepines.[2][3]
Synthesis
[edit]Thio thionamide is even more prone to amidine formation than the lactam itself.
![](https://upload.wikimedia.org/wikipedia/commons/thumb/4/4a/Uldazepam_synthesis.svg/700px-Uldazepam_synthesis.svg.png)
Reaction of thionamide (2) with O-allyl-hydroxylamine gave the oximino (3) uldazepam.
See also
[edit]References
[edit]- ^ "Uldazepam U 31920". Psychotropics. Retrieved 12 June 2013.
- ^ Oelschläger H, Ellaithy MM, Volke J (February 1988). "[Mechanism of the polarographic reduction of the tranquilizer uldazepam]". Archiv der Pharmazie (in German). 321 (2): 69–72. doi:10.1002/ardp.19883210205. PMID 3369929. S2CID 96356746.
- ^ Itil TM, Akpinar S, Ozkut H, Balki N, Herrmann WM (June 1974). "Clinical and computerized EEG effects of U-31,920, a new anxiolytic". Current Therapeutic Research, Clinical and Experimental. 16 (6): 642–54. PMID 4211146.
- ^ DE 2005176, Hester Jr., Jackson Boling, "3H-1,4-benzodiazepine und Verfahren zu deren Herstellung [3H-1,4-benzodiazepines and processes for their preparation]", published 1970-09-10, assigned to The Upjohn Co.