Gomes is a common Portuguese and Old Galician surname. Origin:Visigothic guma, meaning "man", later a first name, Gome and the patronym son of Gome.

• Al Gomes (born 1960), American music producer, music industry strategist, and songwriter
• Albert Gomes (1911–1978), Trinidad and Tobago politician, labour leader and author
• Albino Gomes (born 1994), Indian footballer
• Ana Gomes (born 1954), Portuguese politician
• André Gomes (born 1993), Portuguese footballer
• Angel Gomes (born 2000), English footballer
• Antônio Carlos Gomes (1836–1896), Brazilian composer
• António Gomes Leal (1848–1921), Portuguese poet
• Anthony Gomes (born 1970), Canadian musician
• Bruno Gomes (born 1996), Brazilian footballer
• Chandima Gomes (born 1966), Sri Lankan Sinhala Malaysian engineer, physicist and writer
• Chico (footballer, born 1988), full name Francisco Miguel Franco Antunes Gomes, Portuguese footballer
• Chiquinho Baiano (born 1980), full name Francisco Gomes de Andrade Junior (born 1980), Brazilian footballer.
• Ciro Gomes (born 1957), Brazilian politician, lawyer and academic
• Diogo Gomes (c. 1420–1500), Portuguese navigator and explorer
• Eduardo Gomes (1896–1981), Brazilian soldier and politician
• Egas Gomes de Sousa(1035 -?), Portuguese noble,lord of the house of Felgueiras and Sousa

• Fernão Gomes (15th century), Portuguese explorer and merchant
• Fernando Gomes, several people
• Francis Anthony Gomes (1931–2011), Bangladeshi Roman Catholic bishop
• Francisco Gomes da Rocha, (1745–1808), Brazilian composer
• Francisco Gomes de Amorim, (1827–1891), Portuguese poet and Dramatist
• Francisco da Costa Gomes (1914–2001), Portuguese military officer and politician, the 15th President of the Portuguese Republic
• Francisco Dias Gomes (1745–1795), Portuguese poet and literary critic
• Francisco Luís Gomes, (1829–1869), Indo-Portuguese physician, writer, historian, economist, politician
• Ed Gomes (1936–2020), American politician
• Gomes (footballer, born 1956), Édson Gomes Bonifácio, Brazilian footballer
• Gomes da Costa (footballer), (1919–1987), former Portuguese footballer
• Gomes de Sequeira (16th century), Portuguese explorer
• Gomes Eanes de Zurara (c. 1410–1474), Portuguese chronicler
• Gomes Echigues (1010–1065),Medieval knight,lord of Felgueiras and Governor of the District of Entre-Douro-e-Minho
• Harold Gomes (born 1933), American boxer
• Heurelho Gomes (born 1981), Brazilian footballer
• Jessica Gomes (born 1984), Australian model
• Jonny Gomes (born 1980), American baseball player
• José Alencar Gomes da Silva (1931–2011), Brazilian politician
• Larry Gomes (born 1953), Trinidadian cricketer
• Manoel Gomes (born 1969),Manoel Jardim Gomes,Brazilian singer and composer
• Manuel Teixeira Gomes (1860–1941), Portuguese politician and president of Portugal
• Manuel Gomes da Costa (1863–1929), Portuguese army officer, politician and president of Portugal
• Marcelo Gomes (dancer) (born 1979), Brazilian ballet dancer
• Mário Centeno, full name Mário José Gomes de Freitas Centeno (born 1966), Portuguese economist and politician
• Miguel Gomes (fencer) (born 1972), Portuguese fencer

• Nácia Gomes (1925–2011), Cape Verdean singer
• Nádia Gomes (born 1996), Portuguese footballer
• Nito Gomes (born 2002), Bissau-Guinean footballer
• Nuno Gomes (born 1976), Portuguese footballer
• Nuno Gomes (diver) (20th/21st century), Portuguese-born South African Scuba Diver
• Peter J. Gomes (1942–2011), American clergyman
• Pedro Gomes (triathlete) (born 1983), Portuguese triathlete
• Ralph Gomes (1937–2020), Guyanese track and field athlete
• Ryan Gomes (born 1982), American basketball player
• Soeiro Pereira Gomes (1909–1949), Portuguese writer
• Steve Anthony (born 1959 as Stephen Anthony Gomes), Canadian broadcaster
• Sumana Gomes (born 1968), Sri Lankan cinema actress
• Venceslau Brás Pereira Gomes (1868–1966), Brazilian politician and president of Brazil
• Weasley Gomes de Olivera (born 1962), Brazilian footballer
• Yan Gomes (born 1987), Brazilian American baseball player

• Dr Francisco Luis Gomes District Library, the major library in the district of South Goa, Goa, India
• Gomes Elementary School, a school in Fremont, California

• Pedro Gomes, a municipality in Mato Grosso do Sul, Brazil

• Gómez, a common Spanish surname
• Gomis, variant spelling