| glucose-fructose oxidoreductase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.1.99.28 | ||||||||
| CAS no. | 94949-35-6 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
In enzymology, a glucose-fructose oxidoreductase (EC 1.1.99.28) is an enzyme that catalyzes the chemical reaction
- D-glucose + D-fructose D-gluconolactone + D-glucitol
Thus, the two substrates of this enzyme are D-glucose and D-fructose, whereas its two products are D-gluconolactone and D-glucitol.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with other acceptors. The systematic name of this enzyme class is D-glucose:D-fructose oxidoreductase.
Structural studies[edit]
As of late 2007, 7 structures have been solved for this class of enzymes, with PDB accession codes 1H6A, 1H6B, 1H6C, 1H6D, 1OFG, 1RYD, and 1RYE.
References[edit]
- Zachariou M; Scopes RK (1986). "Glucose-fructose oxidoreductase: a new enzyme isolated from Zymomonas mobilis that is responsible for sorbitol production". J. Bacteriol. 167 (3): 863–869. doi:10.1128/JB.167.3.863-869.1986. PMC 215953. PMID 3745122.
- Hardman MJ, Scopes RK (1988). "The kinetics of glucose-fructose oxidoreductase from Zymomonas mobilis". Eur. J. Biochem. 173 (1): 203–9. doi:10.1111/j.1432-1033.1988.tb13985.x. PMID 3356190.
- Kanagasundaram V, Scopes RK (1992). "Cloning, sequence analysis, and expression of the structural gene encoding glucose-fructose oxidoreductase from Zymomonas mobilis". J. Bacteriol. 174 (5): 1439–47. doi:10.1128/jb.174.5.1439-1447.1992. PMC 206538. PMID 1537789.
