This is a list of famous people who were born, spent a majority of their life, or currently live in Tijuana, Baja California, Mexico.

• Alejandro Amaya, bullfighter
• Fernando Arce, professional football player (Originally from Mérida, Yucatán)

• Beatriz Adriana, singer (Originally from Navojoa, Sonora)
• Brandon Moreno, UFC Flyweight Champion

• Jorge Campillo, professional baseball player
• Laura Caro, singer-songwriter and actress

• Lupita D'Alessio, singer
• Jean Dawson, musician

• Juan Jose Estrada, professional boxer

• Ana Gabriel, singer
• Alejandro Garcia, professional boxer
• El Generico, professional wrestler (Originally from Laval, Quebec, Canada)
• Benji Gil, professional baseball player
• Adrián González, professional baseball player (Originally from San Diego, California, United States of America)
• Edgar Gonzalez, professional baseball player (Originally from San Diego, California, United States of America)

• Alejandro Hernandez, professional tennis player

• Frankie J, rapper
• Héctor Jiménez, actor

• Alejandro Kirk, professional baseball player

• Esteban Loaiza, professional baseball player

• Antonio Margarito, professional boxer (Originally from Torrance, California, United States of America)
• Paloma Márquez, actress
• Manuel Medina, professional boxer (Originally from Tecuala, Nayarit)
• Ricardo Menéndez March, New Zealand politician
• Rey Misterio, professional wrestler
• Erik Morales, professional boxer
• Brandon Moreno, professional mixed martial artist, first Mexican-born UFC Champion.
• Agustin Murillo, professional baseball player
• Rey Mysterio, Jr., professional wrestler (Originally from Chula Vista, California, United States of America)
• Felicia Mercado, Movies and TV Actress, Miss Mexico 1977

• Raúl Pérez, professional boxer
• Tony Perry, guitarist of Pierce the Veil
• Javier Plascencia, Mexican chef

• Victor Regalado, professional golfer
• Marco Antonio Regil, television host
• Tlaloc Rivas, theatre director, writer, and professor
• Oscar Robles, professional baseball player
• Julio E. Rubio, researcher and administrator at Tecnológico de Monterrey

• Rafael Saavedra, writer, DJ
• Freddy Sandoval, professional baseball player
• Carlos Santana, musician (Originally from Autlán, Jalisco)
• Jose Silva, professional baseball player

• Jorge Torres Nilo, professional football player
• Thunder Rosa, professional wrestler

• Julieta Venegas, singer (Originally from Long Beach, California, United States of America)
• Raúl Pompa Victoria, Mexican politician (Institutional Revolutionary Party).

• Gabino Zavala, retired Roman Catholic bishop of the Archdiocese of Los Angeles, father of two children