Holy Family is a Christian term for Jesus, the Virgin Mary and St. Joseph.

Holy Family may also refer to:

• The Holy Family (book), by Karl Marx and Friedrich Engels written in 1844

• Category:Paintings of the Holy Family
• The Holy Family with the Dragonfly, a 1495 engraving by German artist Albrecht Dürer
• Holy Family and donors (Carpaccio), a 1505 painting by Italian artist Vittore Carpaccio
• Doni Tondo, a circa 1507 (probably between 1503 and 1508) painting by Michelangelo
• Canigiani Holy Family (Raphael), a 1508 painting by Italian artist Raphael
• Holy family and Saints (Pontormo), a 1516 painting by Italian artist Jacopo Pontormo
• Holy Family with Saint John the Baptist and Saint Catherine, a. c. 1520–1528 painting by Palma Vecchio and Titian
• Holy Family (Andrea del Sarto), a 1529 painting by Italian artist Andrea Sarto
• The Holy Family with Saint John the Baptist and an Angel, a c. 1535–1540 oil on panel painting by Il Sodoma
• The Holy Family with Saint John the Baptist, a c. 1550–1560 oil on panel painting by Nosadella
• Holy Family (Costa), a 16th-century painting by Italian artist Lorenzo Costa
• Holy Family (El Greco, Museo de Santa Cruz), a 1588 painting by Greek artist El Greco
• Holy Family (El Greco, Hospital de Tavera), a 1595 painting by Greek artist El Greco
• The Holy Family with Angels, 1645 painting by Dutch artist Rembrandt
• The Holy Family (Collinson painting), an 1878 painting by British artist James Collinson

• The Holy Family (film), a 2006 television drama film

• Holy Family (TV series), a 2022 television series

• Holy Family Cathedral (disambiguation)
• Holy Family Church (disambiguation)
• Holy Family Shrine

• Holy Family Catholic High School (disambiguation)
• Holy Family High School (disambiguation)
• Holy Family School (disambiguation)

• Holy Family Academy (Philippines), a K-12 school in Angeles City

• Holy Family Catholic Academy, a secondary school in Cleethorpes, Lincolnshire, England, now Beacon Academy, Cleethorpes
• Holy Family Roman Catholic and Church of England College, a secondary school in Heywood, Greater Manchester, England

• Holy Family Academy (New Hampshire), a junior/ senior high school in Manchester
• Holy Family Academy (Bayonne, New Jersey), a high school
• Holy Family University, Pennsylvania, near Philadelphia