Anticardiolipin antibodies (ACA) directed not to cardiolipin but to a plasma protein cofactor M Galli, T Barbui, P Comfurius, C Maassen, HC Hemker, RFA Zwaal, ... The Lancet 335 (8705), 1544-1547, 1990 | 1768 | 1990 |
Calibrated automated thrombin generation measurement in clotting plasma HC Hemker, P Giesen, R Al Dieri, V Regnault, E De Smedt, ... Pathophysiology of haemostasis and thrombosis 33 (1), 4-15, 2003 | 1638 | 2003 |
Binding of vascular anticoagulant alpha (VAC alpha) to planar phospholipid bilayers. HA Andree, CP Reutelingsperger, R Hauptmann, HC Hemker, ... Journal of Biological Chemistry 265 (9), 4923-4928, 1990 | 887 | 1990 |
Cell-derived microparticles circulate in healthy humans and support low grade thrombin generation RJ Berckmans, R Nieuwland, AN Böing, FP Romijn, CE Hack, A Sturk Thrombosis and haemostasis 85 (04), 639-649, 2001 | 861 | 2001 |
The role of phospholipids and factor Va in the prothrombinase complex. J Rosing, G Tans, JWP Govers-Riemslag, RF Zwaal, HC Hemker Journal of Biological Chemistry 255 (1), 274-283, 1980 | 831 | 1980 |
The calibrated automated thrombogram (CAT): a universal routine test for hyper-and hypocoagulability HC Hemker, P Giesen, R AlDieri, V Regnault, E De Smed, R Wagenvoord, ... Pathophysiology of haemostasis and thrombosis 32 (5-6), 249-253, 2002 | 816 | 2002 |
The role of phospholipid and factor VIIIa in the activation of bovine factor X. G van Dieijen, G Tans, J Rosing, HC Hemker Journal of Biological Chemistry 256 (7), 3433-3442, 1981 | 749 | 1981 |
Generation of prothrombin‐converting activity and the exposure of phosphatidylserine at the outer surface of platelets EM Bevers, P Comfurius, JLML van Rijn, HC Hemker, F Robert, A ZWAAL European journal of biochemistry 122 (2), 429-436, 1982 | 664 | 1982 |
Thrombin generation, a function test of the haemostaticthrombotic system HC Hemker, R Al Dieri, E De Smedt, S Béguin Thrombosis and haemostasis 96 (11), 553-561, 2006 | 606 | 2006 |
Inhibition of platelet-mediated, tissue factor-induced thrombin generation by the mouse/human chimeric 7E3 antibody. Potential implications for the effect of c7E3 Fab treatment … JC Reverter, S Beguin, H Kessels, R Kumar, HC Hemker, BS Coller The Journal of clinical investigation 98 (3), 863-874, 1996 | 518 | 1996 |
Oral contraceptives and venous thrombosis: different sensitivities to activated protein C in women using second‐and third‐generation oral contraceptives J Rosing, G Tans, GAF Nicolaes, M Thomassen, R Van Oerle, ... British journal of haematology 97 (1), 233-238, 1997 | 463 | 1997 |
The adsorption of prothrombin to phosphatidylserine multilayers quantitated by ellipsometry. PA Cuypers, JW Corsel, MP Janssen, JM Kop, WT Hermens, HC Hemker Journal of Biological Chemistry 258 (4), 2426-2431, 1983 | 462 | 1983 |
Continuous registration of thrombin generation in plasma, its use for the determination of the thrombin potential HC Hemker, S Wielders, H Kessels, S Beguin Thrombosis and haemostasis 70 (10), 617-624, 1993 | 454 | 1993 |
Thrombin generation in plasma: its assessment via the endogenous thrombin potential HC Hemker, S Béguin Thrombosis and haemostasis 74 (07), 134-138, 1995 | 413 | 1995 |
The majority of circulating platelet-derived microparticles fail to bind annexin V, lack phospholipid-dependent procoagulant activity and demonstrate greater expression of … DE Connor, T Exner, DDF Ma, JE Joseph Thrombosis and haemostasis 103 (05), 1044-1052, 2010 | 400 | 2010 |
The thrombogram: monitoring thrombin generation in platelet rich plasma CH Hemker, PLA Giesen, M Ramjee, R Wagenvoord, S Béguin Thrombosis and haemostasis 83 (04), 589-591, 2000 | 385 | 2000 |
Evaluation of thrombin generating capacity in plasma from patients with haemophilia A and B Y Dargaud, S Béguin, A Lienhart, R Al Dieri, C Trzeciak, JC Bordet, ... Thrombosis and haemostasis 93 (03), 475-480, 2005 | 383 | 2005 |
The thrombogram in rare inherited coagulation disorders: its relation to clinical bleeding R Al Dieri, F Peyvandi, E Santagostino, M Giansily, PM Mannucci, ... Thrombosis and haemostasis 88 (10), 576-582, 2002 | 351 | 2002 |
A computer assisted method to obtain the prothrombin activation velocity in whole plasma independent of thrombin decay processes HC Hemker, GM Willems, S Beguin Thrombosis and haemostasis 56 (04), 009-017, 1986 | 348 | 1986 |
Nonanticoagulant heparin prevents histone-mediated cytotoxicity in vitro and improves survival in sepsis KCAA Wildhagen, P García de Frutos, CP Reutelingsperger, R Schrijver, ... Blood, The Journal of the American Society of Hematology 123 (7), 1098-1101, 2014 | 310 | 2014 |