Second City or The Second City may refer to:

• Second city of the United Kingdom
• Chicago, nicknamed the Second City
• The Second City, an improvisational comedy troupe initially based in Chicago
• Mercenary: The Second City, a 1986 expansion pack for the video game Mercenary
• "Second City", an episode of 2007 Canadian/American TV series The Dresden Files
• Second City derby, Association-football rivalry between Aston Villa and Birmingham City
• Secondcity, stage name of American-born British musician Rowan Harrington (born 1987)

See also[edit]

• Second City Television, a Canadian television sketch comedy show that aired intermittently between 1976 and 1984
• Secondary city