A nice guy is an informal term for a male who is perceived or portrays himself as agreeable.
Nice Guy may also refer to:
- Nice Guy (album), by American country musician Eric Paslay, or its title song
- "Nice Guy" (song), by American hip hop rapper Eminem
- "Nice Guy", a 2012 song by Lukas Graham from Lukas Graham
- An alternative name for the South Korean TV series The Innocent Man