Durham City or City of Durham may refer to:
- England
- Durham, England, the county town of County Durham
- Durham District, a former local government district, which held city status 1974-2009
- Durham and Framwelgate, a former local government district, which held city status until 1974
- City of Durham (parish), a civil parish
- City of Durham (UK Parliament constituency)
- Durham City A.F.C., a football team
- Durham City RFC, a rugby union team
- North America