Andrew Cooper may refer to:
- Andy Cooper (1898–1941), American baseball player
- Andrew W. Cooper (1927–2002), American civil rights activist and journalist
- Andrew F. Cooper (born 1950), Canadian political scientist
- Andrew Cooper III, modelling pseudonym of American actor and model Sam J. Jones (born 1954)
- Andrew Cooper, Baron Cooper of Windrush (born 1963), British Conservative politician
- Andrew Cooper (rower) (born 1964), Australian Olympic rower
- Andrew Ian Cooper, British chemist
- Andrew Cooper (actor) (born 1981), British actor and model
- Andrew Cooper (councillor), councillor in Tamworth and candidate for the 2023 Tamworth by-election
- Andrew Cooper (The Inbetweeners), fictional character in the British sitcom The Inbetweeners