Vuksanović (Serbian Cyrillic: Вуксановић) is a predominantly Serbian surname, a patronymic derived from the given name Vuksan. It may refer to:

• Boško Vuksanović (1928–2011), Yugoslav water polo player
• Divna M. Vuksanović (born 1965), Serbian philosopher, writer, media theorist
• Draginja Vuksanović, Montenegrin politician and University professor
• Momčilo Vuksanović (born 1955), Serb NGO activist from Montenegro
• Oliver Vuksanović (born 1966), Macedonian lawyer
• Sanja Vuksanović (born 1967), Serbian chess player with title of Woman Grandmaster
• Slobodan Vuksanović (born 1965), Serbian writer and politician
• Sretko Vuksanović (born 1973), Bosnian retired footballer
• Vladimir Vuksanović (born 1978), Serbian basketball player
• Zoran Vuksanović (born 1972), Montenegrin retired footballer
• Žikica Vuksanović (born 1974), Slovenian retired footballer