GABRP
Identifiers
Aliases	GABRP, gamma-aminobutyric acid type A receptor pi subunit, gamma-aminobutyric acid type A receptor subunit pi
External IDs	OMIM: 602729 MGI: 2387597 HomoloGene: 22798 GeneCards: GABRP
Gene location (Human) Chr. Chromosome 5 (human)[1] Band 5q35.1 Start 170,763,350 bp[1] End 170,814,047 bp[1]
Gene location (Mouse) Chr. Chromosome 11 (mouse)[2] Band 11|11 A4 Start 33,500,781 bp[2] End 33,528,959 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in Top expressed in More reference expression data BioGPS More reference expression data
Gene ontology Molecular function Cellular component Biological process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 2568 216643 Ensembl ENSG00000094755 ENSMUSG00000020159 UniProt O00591 Q8QZW7 RefSeq (mRNA) NM_001291985 NM_014211 NM_146017 RefSeq (protein) NP_001278914 NP_055026 NP_666129 Location (UCSC) Chr 5: 170.76 – 170.81 Mb Chr 11: 33.5 – 33.53 Mb PubMed search [3] [4]
Wikidata
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Gamma-aminobutyric acid receptor subunit pi is a protein that in humans is encoded by the GABRP gene.^[5][6]

The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. The subunit encoded by this gene is expressed in several non-neuronal tissues including the uterus and ovaries. This subunit can assemble with known GABA A receptor subunits, and the presence of this subunit alters the sensitivity of recombinant receptors to modulatory agents such as pregnanolone.^[6]

See also[edit]

• GABAA receptor

References[edit]

Further reading[edit]

External links[edit]

• GABRP+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.