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(1,2,5,6-Tetrahydropyridin-4-yl)­methylphosphinic acid
Names
Preferred IUPAC name
Methyl(1,2,3,6-tetrahydropyridin-4-yl)phosphinic acid
Other names
TPMPA
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
UNII
  • InChI=1S/C6H12NO2P/c1-10(8,9)6-2-4-7-5-3-6/h2,7H,3-5H2,1H3,(H,8,9) checkY
    Key: MFUKVPOVVKKLRQ-UHFFFAOYSA-N checkY
  • InChI=1/C6H12NO2P/c1-10(8,9)6-2-4-7-5-3-6/h2,7H,3-5H2,1H3,(H,8,9)
    Key: MFUKVPOVVKKLRQ-UHFFFAOYAY
  • CP(=O)(C1=CCNCC1)O
  • O=P([O-])(/C1=C/C[NH2+]CC1)C
Properties
C6H12NO2P
Molar mass 161.141 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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(1,2,5,6-Tetrahydropyridin-4-yl)methylphosphinic acid (TPMPA) is a GABA antagonist selective for the GABAA-ρ (previously known as GABAC) subtype.[1]

References[edit]

  1. ^ Li, Shifeng; Zhang, Yunbin; Liu, Haixiong; Yan, Yuanchang; Li, Yiping (2008). "Identification and expression of GABACreceptor in rat testis and spermatozoa". Acta Biochimica et Biophysica Sinica. 40 (8): 761–7. doi:10.1111/j.1745-7270.2008.00453.x. PMID 18685793.


source: https://en.wikipedia.org/wiki/(1,2,5,6-Tetrahydropyridin-4-yl)methylphosphinic_acid

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