THC Science

O-4310
Identifiers
	IUPAC name 3-[2-(dimethylamino)ethyl]-6-fluoro-1-isopropyl-1H-indol-4-ol;
CAS Number	885671-63-6 ;
PubChem CID	68541087;
ChemSpider	65322014;
UNII	EJ3AE64233;
Chemical and physical data
Formula	C15H21FN2O
Molar mass	264.344 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC(C)N1C2=CC(F)=CC(O)=C2C(CCN(C)C)=C1;
	InChI InChI=1S/C15H21FN2O/c1-10(2)18-9-11(5-6-17(3)4)15-13(18)7-12(16)8-14(15)19/h7-10,19H,5-6H2,1-4H3; Key:PAUIFMSQKOHMQT-UHFFFAOYSA-N;

O-4310 (1-isopropyl-6-fluoro-psilocin) is a tryptamine derivative developed by Organix Inc which acts as a serotonin receptor agonist. It is claimed to have an EC₅₀ of 5nM at 5-HT_2A with 89% efficacy vs 5-HT, and 100x selectivity over 5-HT_2C, while being apparently inactive at the 5-HT_2B antitarget.^[1]

References[edit]

^ US 7655691, Kumaran G, Morency C, Roth B, Sard HP, Shuster L Xu L, "Indole compounds useful as serotonin selective agents.", published 11 May 2006, assigned to Organix Inc

Identifiers

IUPAC name 3-[2-(dimethylamino)ethyl]-6-fluoro-1-isopropyl-1H-indol-4-ol
CAS Number	885671-63-6^Y
PubChem CID	68541087
ChemSpider	65322014
UNII	EJ3AE64233
Chemical and physical data
Formula	C₁₅H₂₁FN₂O
Molar mass	264.344 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES CC(C)N1C2=CC(F)=CC(O)=C2C(CCN(C)C)=C1
InChI InChI=1S/C15H21FN2O/c1-10(2)18-9-11(5-6-17(3)4)15-13(18)7-12(16)8-14(15)19/h7-10,19H,5-6H2,1-4H3 Key:PAUIFMSQKOHMQT-UHFFFAOYSA-N