THC Science

GPR68
Identifiers
Aliases	GPR68, GPR12A, OGR1, G protein-coupled receptor 68, AI2A6
External IDs	OMIM: 601404 MGI: 2441763 HomoloGene: 2603 GeneCards: GPR68
Gene location (Human)
Chr.	Chromosome 14 (human)
End	91,253,925 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	100,874,457 bp
RNA expression pattern
	Top expressed in
	Top expressed in
	More reference expression data
	More reference expression data
Gene ontology
Molecular function
Cellular component
Biological process
	Sources:Amigo / QuickGO
Orthologs
	8111
	238377
	ENSG00000119714
	ENSMUSG00000047415
	Q15743
	Q8BFQ3
	NM_001177676; NM_003485; NM_001348437
	NM_001177673; NM_001177674; NM_175493
	NP_001171147; NP_003476; NP_001335366
	NP_001171144; NP_001171145; NP_780702; NP_001390243
	Wikidata
View/Edit Human	View/Edit Mouse

Ovarian cancer G-protein coupled receptor 1 is a protein that in humans is encoded by the GPR68 gene.^[5]^[6]

References[edit]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000119714 - Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000047415 - Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Xu Y, Casey G (Sep 1996). "Identification of human OGR1, a novel G protein-coupled receptor that maps to chromosome 14". Genomics. 35 (2): 397–402. doi:10.1006/geno.1996.0377. PMID 8661159.
^ "Entrez Gene: GPR68 G protein-coupled receptor 68".

Further reading[edit]

Xu Y (2002). "Sphingosylphosphorylcholine and lysophosphatidylcholine: G protein-coupled receptors and receptor-mediated signal transduction". Biochim. Biophys. Acta. 1582 (1–3): 81–8. doi:10.1016/S1388-1981(02)00140-3. PMID 12069813.
An S, Tsai C, Goetzl EJ (1996). "Cloning, sequencing and tissue distribution of two related G protein-coupled receptor candidates expressed prominently in human lung tissue". FEBS Lett. 375 (1–2): 121–4. doi:10.1016/0014-5793(95)01196-L. PMID 7498459. S2CID 9845527.
Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Ludwig MG, Vanek M, Guerini D, et al. (2003). "Proton-sensing G-protein-coupled receptors". Nature. 425 (6953): 93–8. Bibcode:2003Natur.425...93L. doi:10.1038/nature01905. PMID 12955148. S2CID 4395698.
Bektas M, Barak LS, Jolly PS, et al. (2003). "The G protein-coupled receptor GPR4 suppresses ERK activation in a ligand-independent manner". Biochemistry. 42 (42): 12181–91. doi:10.1021/bi035051y. PMID 14567679.
Brandenberger R, Wei H, Zhang S, et al. (2005). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation". Nat. Biotechnol. 22 (6): 707–16. doi:10.1038/nbt971. PMID 15146197. S2CID 27764390.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Radu CG, Nijagal A, McLaughlin J, et al. (2005). "Differential proton sensitivity of related G protein-coupled receptors T cell death-associated gene 8 and G2A expressed in immune cells". Proc. Natl. Acad. Sci. U.S.A. 102 (5): 1632–7. Bibcode:2005PNAS..102.1632R. doi:10.1073/pnas.0409415102. PMC 545089. PMID 15665078.
Tomura H, Wang JQ, Komachi M, et al. (2005). "Prostaglandin I(2) production and cAMP accumulation in response to acidic extracellular pH through OGR1 in human aortic smooth muscle cells". J. Biol. Chem. 280 (41): 34458–64. doi:10.1074/jbc.M505287200. PMID 16087674.
Singh LS, Berk M, Oates R, et al. (2007). "Ovarian cancer G protein-coupled receptor 1, a new metastasis suppressor gene in prostate cancer". J. Natl. Cancer Inst. 99 (17): 1313–27. doi:10.1093/jnci/djm107. hdl:10536/DRO/DU:30094039. PMID 17728215.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000119714 - Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000047415 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8661159-5] Xu Y, Casey G (Sep 1996). "Identification of human OGR1, a novel G protein-coupled receptor that maps to chromosome 14". Genomics. 35 (2): 397–402. doi:10.1006/geno.1996.0377. PMID 8661159.

[entrez-6] "Entrez Gene: GPR68 G protein-coupled receptor 68".

[1]

[2]

[3]

[4]

[5]

[6]

THC Science

Bringing Science to the Cannabis Conversation!

Cannabis Ruderalis

See also[edit]

References[edit]

Further reading[edit]

Leave a Reply