Tilmacoxib

Pharmacokinetic data
Bioavailability	solution (64–88%) compared with capsule (22–40%).
Identifiers
IUPAC name 4-(4-cyclohexyl-2-methyl-1,3-oxazol-5-yl)-2-fluorobenzenesulfonamide
CAS Number	180200-68-4 Y
PubChem CID	159271
ChemSpider	140082
UNII	G6VI5P84SX
ChEBI	CHEBI:73041 Y
ChEMBL	ChEMBL34913
CompTox Dashboard (EPA)	DTXSID0057671
Chemical and physical data
Formula	C16H19FN2O3S
Molar mass	338.40 g·mol−1
3D model (JSmol)	Interactive image
SMILES O=S(=O)(N)c3ccc(c1oc(nc1C2CCCCC2)C)cc3F
InChI InChI=1S/C16H19FN2O3S/c1-10-19-15(11-5-3-2-4-6-11)16(22-10)12-7-8-14(13(17)9-12)23(18,20)21/h7-9,11H,2-6H2,1H3,(H2,18,20,21) Key:MIMJSJSRRDZIPW-UHFFFAOYSA-N

Tilmacoxib or JTE-522 is a COX-2 inhibitor and is an effective chemopreventive agent against rat experimental liver fibrosis.^[1]

See also[edit]

• NS-398
• Celecoxib

References[edit]