Protein-coding gene in the species Homo sapiens
G protein-coupled receptor 1 , also known as GPR1 , is a protein that in humans is encoded by the GPR1 gene .[5] [6]
GPR1 is a member of the G protein-coupled receptor family of transmembrane receptors. It functions as a receptor for chemerin .[7] CMKLR1 and CCRL2 .
References [ edit ]
^ a b c ENSG00000283448 GRCh38: Ensembl release 89: ENSG00000183671, ENSG00000283448 - Ensembl , May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000046856 - Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Entrez Gene: GPR1 G protein-coupled receptor 1" .^ Marchese A, Docherty JM, Nguyen T, Heiber M, Cheng R, Heng HH, Tsui LC, Shi X, George SR, O'Dowd BF (October 1994). "Cloning of human genes encoding novel G protein-coupled receptors". Genomics . 23 (3): 609–18. doi :10.1006/geno.1994.1549 . PMID 7851889 . ^ Barnea G, Strapps W, Herrada G, Berman Y, Ong J, Kloss B, Axel R, Lee KJ (January 2008). "The genetic design of signaling cascades to record receptor activation" . Proc. Natl. Acad. Sci. U.S.A . 105 (1): 64–9. doi :10.1073/pnas.0710487105 PMC 2224232 PMID 18165312 .
Further reading [ edit ]
Shimizu N, Soda Y, Kanbe K, et al. (1999). "An Orphan G Protein-Coupled Receptor, GPR1, Acts as a Coreceptor To Allow Replication of Human Immunodeficiency Virus Types 1 and 2 in Brain-Derived Cells" . J. Virol . 73 (6): 5231–9. doi :10.1128/JVI.73.6.5231-5239.1999 . PMC 112576 PMID 10233994 . Tokizawa S, Shimizu N, Hui-Yu L, et al. (2000). "Infection of mesangial cells with HIV and SIV: identification of GPR1 as a coreceptor" . Kidney Int . 58 (2): 607–17. doi :10.1046/j.1523-1755.2000.00207.x PMID 10916084 . Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903. Bibcode :2002PNAS...9916899M . doi :10.1073/pnas.242603899 PMC 139241 PMID 12477932 . Kang MK, Kameta A, Shin KH, et al. (2003). "Senescence-associated genes in normal human oral keratinocytes". Exp. Cell Res . 287 (2): 272–81. doi :10.1016/S0014-4827(03)00061-2 . PMID 12837283 . Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7. doi :10.1101/gr.2596504 . PMC 528928 PMID 15489334 . Hillier LW, Graves TA, Fulton RS, et al. (2005). "Generation and annotation of the DNA sequences of human chromosomes 2 and 4" . Nature . 434 (7034): 724–31. Bibcode :2005Natur.434..724H . doi :10.1038/nature03466 PMID 15815621 . Jinno-Oue A, Shimizu N, Soda Y, et al. (2005). "The synthetic peptide derived from the NH2-terminal extracellular region of an orphan G protein-coupled receptor, GPR1, preferentially inhibits infection of X4 HIV-1" . J. Biol. Chem . 280 (35): 30924–34. doi :10.1074/jbc.M500195200 PMID 15919664 . Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries" . DNA Res . 12 (2): 117–26. doi :10.1093/dnares/12.2.117 PMID 16303743 . Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes" . Genome Res . 16 (1): 55–65. doi :10.1101/gr.4039406 . PMC 1356129 PMID 16344560 .
