Charles or Charlie Cox may refer to:

• Charles Cox (wrestler) (born 1957), Canadian Olympic wrestler
• Charles E. Cox (1860–1936), Indiana Supreme Court judge
• Charles Frederick Cox (1863–1944), Australian soldier
• Charles Winnans Cox (1882–1958), Canadian politician
• Charles Shipley Cox (1922–2015), American oceanographer
• Charlie Cox (born 1982), English actor
• Charlie Cox (footballer, born 1905) (1905–1978), English footballer
• Charlie Cox (footballer, born 1926) (1926–2008), Scottish footballer
• Charlie Cox (Australian footballer) (1873–1947), Australian rules footballer
• Charlie Cox (racing driver) (born 1960), Australia motor racing commentator
• Bud Cox (born Charles Cox, born 1960), American tennis player
• Sir Charles Cox (brewer) (1660–1729), English brewer and MP
• Charles Cox (businessman) (1731–1808), English businessman active in Harwich, Essex
• Charles Chapman Cox, American economist, appointed to the U.S. Securities and Exchange Commission under Ronald Reagan
• Charles Christopher Cox (born 1952), US politician and financial regulator
• Charles B. Cox (1810–1891), American businessman and Wisconsin politician

• Charles Coxe (1661–1728), MP for Cirencester, and for Gloucester
• Charles Westley Coxe, MP for Cricklade
• Charles Cocks (disambiguation)