THC Science

SYNJ1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1W80, 2DNR, 2VJ0
Identifiers
Aliases	SYNJ1, INPP5G, PARK20, synaptojanin 1, EIEE53, DEE53
External IDs	OMIM: 604297 MGI: 1354961 HomoloGene: 48252 GeneCards: SYNJ1
Gene location (Human)
Chr.	Chromosome 21 (human)
End	32,728,040 bp
Gene location (Mouse)
Chr.	Chromosome 16 (mouse)
End	90,808,196 bp
RNA expression pattern
	Top expressed in
	Top expressed in
	More reference expression data
	n/a
Gene ontology
Molecular function
Cellular component
Biological process
	Sources:Amigo / QuickGO
Orthologs
	8867
	104015
	ENSG00000159082
	ENSMUSG00000022973
	O43426
	Q8CHC4
	NM_203446; NM_001160302; NM_001160306; NM_003895
	NM_001045515; NM_001164483
	NP_001153774; NP_001153778; NP_003886; NP_982271
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Synaptojanin 1 is a protein that in humans is encoded by the SYNJ1 gene. ^[5]

Function[edit]

This gene encodes a phosphoinositide phosphatase that regulates levels of membrane phosphatidylinositol-4,5-bisphosphate. As such, expression of this enzyme may affect synaptic transmission and membrane trafficking. Multiple transcript variants encoding different isoforms have been found for this gene.

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000159082 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000022973 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: Synaptojanin 1". Retrieved 2016-03-13.