THC Science

Maneb
Names
	IUPAC name [[2-[(Dithiocarboxy)amino]ethyl]carbamodithioato]](2-)-kS,kS']manganese
	Other names Manganese ethylene-1,2-bisdithiocarbamate, polymer
Identifiers
CAS Number	12427-38-2 ;
3D model (JSmol)	Interactive image;
ChemSpider	2297517 ;
ECHA InfoCard	100.032.400
MeSH	Maneb
PubChem CID	3032581;
UNII	K221E12G7T ;
CompTox Dashboard (EPA)	DTXSID9020794 ;
	InChI InChI=1S/C4H8N2S4.Mn/c7-3(8)5-1-2-6-4(9)10;/h1-2H2,(H2,5,7,8)(H2,6,9,10);/q;+2/p-2 Key: YKSNLCVSTHTHJA-UHFFFAOYSA-L;
	SMILES [Mn+]SC(=S)NCCNC(=S)S[Mn]SC(=S)NCCNC(=S)S[Mn]SC(=S)NCCNC(=S)S[Mn]SC(=S)NCCNC(=S)S[Mn]SC(=S)NCCNC(=S)[S-];
Properties
Chemical formula	(C4H6MnN2S4)n
Appearance	Yellow to brown colored crystalline solid
Density	1.92 g/cm3
Melting point	192 to 204 °C (378 to 399 °F; 465 to 477 K) (decomposes)
Solubility in water	160 mg/L
Hazards
	GHS labelling:
Pictograms
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

Maneb is a fungicide and a polymeric complex of manganese with the ethylene bis(dithiocarbamate) anionic ligand.^[1]

Health effects[edit]

Exposure to Maneb can irritate the eyes, nose, and throat. Prolonged or long-term exposure may interfere with the function of the thyroid.^[2]

It can be also used to create a toxin-based animal model of Parkinson's disease, usually in primates.^[3]

It was included in a pesticide ban proposed by the Swedish Chemicals Agency ^[4] and approved by the European Parliament on January 13, 2009.^[5]

^ Arno H. Reidies "Manganese Compounds" Ullmann's Encyclopedia of Chemical Technology 2007; Wiley-VCH, Weinheim. doi:10.1002/14356007.a16_123
^ "MANEB.doc" (PDF).{{cite web}}: CS1 maint: url-status (link)
^ Cicchetti F, Drouin-Ouellet J, Gross RE (September 2009). "Environmental toxins and Parkinson's disease: what have we learned from pesticide-induced animal models?". Trends Pharmacol. Sci. 30 (9): 475–83. doi:10.1016/j.tips.2009.06.005. PMID 19729209.
^ "Interpretation of criteria for approval of active substances in the proposed EU plant protection regulation". Swedish Chemicals Agency (KemI). 2008-09-23. Archived from the original on 2009-01-01. Retrieved 2009-01-14.
^ "MEPs approve pesticides legislation". 2009-01-13. Archived from the original on 2009-01-25. Retrieved 2009-01-14.