A thienodiazepine^[1] is a heterocyclic compound containing a diazepine ring fused to a thiophene ring.

If R₁ and R₂ are part of a triazole ring, the substance is called a "thienotriazolodiazepine."

The thienodiazepine structure forms the central core of some pharmaceutical and recreational drugs, including:

• Bentazepam
• Clotiazepam

Since thienodiazepines interact with the benzodiazepine receptor site, they typically have similar effects as benzodiazepines.

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