Protein-coding gene in the species Homo sapiens
Steroid 5-alpha-reductase 3 , also known as 3-oxo-5-alpha-steroid 4-dehydrogenase 3 , is an enzyme that in humans is encoded by the SRD5A3 gene .[5] [6] 5α-reductase .
See also [ edit ] References [ edit ]
^ a b c GRCh38: Ensembl release 89: ENSG00000128039 – Ensembl , May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000029233 – Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Entrez Gene: steroid 5 alpha-reductase 3" .^ Uemura M, Tamura K, Chung S, Honma S, Okuyama A, Nakamura Y, Nakagawa H (January 2008). "Novel 5 alpha-steroid reductase (SRD5A3, type-3) is overexpressed in hormone-refractory prostate cancer" . Cancer Sci . 99 (1): 81–6. doi :10.1111/j.1349-7006.2007.00656.x PMID 17986282 . S2CID 51733620 .
Further reading [ edit ]
Payne AH, Hales DB (2004). "Overview of steroidogenic enzymes in the pathway from cholesterol to active steroid hormones" . Endocr. Rev . 25 (6): 947–70. doi :10.1210/er.2003-0030 PMID 15583024 . Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903. Bibcode :2002PNAS...9916899M . doi :10.1073/pnas.242603899 PMC 139241 PMID 12477932 . Cantagrel V, Lefeber DJ, Ng BG, et al. (2010). "SRD5A3 is required for converting polyprenol to dolichol and is mutated in a congenital glycosylation disorder" . Cell . 142 (2): 203–17. doi :10.1016/j.cell.2010.06.001 . PMC 2940322 PMID 20637498 . Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs" . Nat. Genet . 36 (1): 40–5. doi :10.1038/ng1285 PMID 14702039 .
Activity Regulation Classification Kinetics Types
