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Odontoma
Other namesOdontome[1][2][3]
SpecialtyDentistry

An odontoma, also known as an odontome, is a benign tumour[4] linked to tooth development.[5] Specifically, it is a dental hamartoma, meaning that it is composed of normal dental tissue that has grown in an irregular way. It includes both odontogenic hard and soft tissues.[1] As with normal tooth development, odontomas stop growing once mature which makes them benign.[6]

The average age of people found with an odontoma is 14.[7] The condition is frequently associated with one or more unerupted teeth and is often detected through failure of teeth to erupt at the expected time. Though most cases are found impacted within the jaw there are instances where odontomas have erupted into the oral cavity.[8]

Types[edit]

There are two main types: compound and complex.[9]

  • A compound odontoma consists of the four separate dental tissues (enamel, dentine, cementum and pulp) embedded in fibrous connective tissue and surrounded by a fibrous capsule. It may present a lobulated appearance where there is no definitive demarcation of separate tissues between the individual "toothlets" (or denticles). Compound odontomas are usually found in the anterior maxilla and are less than 20mm in diameter.[6]
  • The complex type is unrecognizable as dental hard and soft tissues, usually presenting as a radioopaque area with varying densities indicating presence of enamel. It generally appears in the posterior mandible and can grow to be several centimetres in size. [6][10]

In addition to the above forms, the dilated odontoma is an infrequent developmental alteration that appears in any area of the dental arches and can affect deciduous, permanent and supernumerary teeth. Dens invaginatus is a developmental anomaly resulting from invagination of a portion of crown forming within the enamel organ during odontogenesis. The most extreme form of dens invaginatus is known as a dilated odontoma.

There are two types of lesions which are regarded as complex odontomas with a prominent soft tissue component resembling ameloblastic fibroma. With similar presentation and treatment outcomes to complex odontomas. [6] These lesions were poorly defined previously and were removed as separate entities from the WHO Classification of Head and Neck Tumors (2017). They are now regarded as developing odontomas as histologically there are no differences. [11]

Histopathology[edit]

Odontomas are from mixed epithelial and mesenchymal components which are required for tooth development, producing enamel, dentine, cementum and pulp tissue. [6]

Presentation[edit]

Odontomas usually asymptomatic and present as chance radiographic finding, often during childhood and adolescence when teeth do not erupt within the expected timeframe. [6]

Occasionally odontomas can erupt into the mouth and this can lead to acute infections resembling a dental abscess. [10]

During the early stage of odontoma development; radiolucent flecks develop. At a later stage of development a dense radioopaque mass becomes visible as enamel and dentine forms. [6]

Aetiology[edit]

Overall aetiology is unknown. However, odontomas have been related to local trauma, inflammatory and/or infectious processes, hereditary anomalies such as Gardener's syndrome and Hermanns syndrome, odontoblastic hyperactivity, mature odontoblasts and dental lamina remnants (Cell Rests of Serres). [12]

Gardner's syndrome[edit]

Gardner's syndrome is a subtype of Familial adenomatous polyposis. The clinical presentation of this syndrome includes multiple odontomas. This condition has a high risk of malignancy through adenocarcinoma of the bowel. [10]

Treatment[edit]

Most common treatment is surgical enucleation due to well-encapsulated nature of odontomas allowing separation from surrounding bone. [10][6]

If left untreated can result in a dentigerous cyst. [6][12]

Epidemiology[edit]

Odontomas are thought to be the second most frequent type of odontogenic tumor worldwide (after ameloblastoma), accounting for about 20% of all cases within this relatively uncommon tumor category which shows large geographic variations in incidence. According to the same article discussion, statistics might appear misleading as most of the odontomas within high-occurrence ameloblastoma-areas, are well-likely left unreported due to hospital management problems and asymptomatic clinical picture of odontoma.[13]

In 2019, a 7-year-old boy from Tiruvallur district,[14] near Chennai, India with compound odontoma received surgery to remove 526 teeth from his lower right jaw.[15][16]

References[edit]

  1. ^ a b AK, El-Naggar; JKC, Chan; JR, Grandis; T, Takata; PJ, Slootweg (2017-01-23). WHO Classification of Head and Neck Tumours. ISBN 9789283224389.
  2. ^ Ireland R (25 March 2010). A Dictionary of Dentistry. Oxford University Press. p. 247. ISBN 978-0-19-953301-5.
  3. ^ Fletcher CDM (2 April 2013). Diagnostic Histopathology of Tumors: Expert Consult - Online. Elsevier Health Sciences. p. 791. ISBN 978-1-4557-3754-3.
  4. ^ Junquera L, de Vicente JC, Roig P, Olay S, Rodríguez-Recio O (2005). "Intraosseous odontoma erupted into the oral cavity: an unusual pathology" (PDF). Medicina Oral, Patologia Oral y Cirugia Bucal. 10 (3): 248–51. PMID 15876969.
  5. ^ "Odontoma". Dorland's Illustrated Medical Dictionary. Elsevier Health Sciences. 2011. p. 1313. ISBN 978-1-4160-6257-8.
  6. ^ a b c d e f g h i Cawson, R. A. (2017). Cawson's Essentials of Oral Pathology and Oral Medicine. Odell, E. W. (9th ed.). London: Elsevier Health Sciences UK. ISBN 978-0-7020-7391-5. OCLC 1119449255.
  7. ^ "Odontogenic tumors". Archived from the original on 2011-07-20. Retrieved 2009-01-04.
  8. ^ Bhargavan Sarojini S, Khosla E, Varghese T, Johnson Arakkal L (2014). "Eruption of odontomas into the oral cavity: a report of 2 cases". Case Reports in Dentistry. 2014: 639173. doi:10.1155/2014/639173. PMC 4037568. PMID 24900927.
  9. ^ Amado Cuesta S, Gargallo Albiol J, Berini Aytés L, Gay Escoda C (2003). "Review of 61 cases of odontoma. Presentation of an erupted complex odontoma" (PDF). Medicina Oral. 8 (5): 366–73. PMID 14595262.
  10. ^ a b c d Coulthard, Paul. (2013). Master Dentistry : Volume 1: Oral and Maxillofacial Surgery, Radiology, Pathology and Oral Medicine. Horner, Keith., Sloan, Philip., Theaker, Elizabeth D. (3rd ed.). London: Elsevier Health Sciences UK. ISBN 978-0-7020-5557-7. OCLC 884647370.
  11. ^ Speight PM, Takata T (March 2018). "New tumour entities in the 4th edition of the World Health Organization Classification of Head and Neck tumours: odontogenic and maxillofacial bone tumours". Virchows Archiv. 472 (3): 331–339. doi:10.1007/s00428-017-2182-3. PMC 5886999. PMID 28674741.
  12. ^ a b Satish V, Prabhadevi MC, Sharma R (September 2011). "Odontome: A Brief Overview". International Journal of Clinical Pediatric Dentistry. 4 (3): 177–85. doi:10.5005/jp-journals-10005-1106. PMC 5034075. PMID 27678223.
  13. ^ Avelar RL, Primo BT, Pinheiro-Nogueira CB, Studart-Soares EC, de Oliveira RB, Romulo de Medeiros J, Hernandez PA (November 2011). "Worldwide incidence of odontogenic tumors". The Journal of Craniofacial Surgery. 22 (6): 2118–23. doi:10.1097/SCS.0b013e3182323cc7. PMID 22067866. S2CID 5286887.
  14. ^ Chennai dentists extract 526 teeth from mouth of seven-year-old boy, 31 July 2019, New Indian Express.
  15. ^ Dunham J (August 1, 2019). "Boy has surgery to remove 526 teeth 'reminiscent of pearls in an oyster'". CTV News. Retrieved 3 August 2019.
  16. ^ Saavetha's Surgical and Pathological Excellence in Unmasking 256 Teeth from a Single Site in a Child, 1 August 2019 News from Saavetha Dental College, Chennai. It features photographs and X-ray pictures.

External links[edit]

source: https://en.wikipedia.org/wiki/Odontoma

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