Limostatin (from Limos, the Greek goddess of starvation) is a peptide hormone found in Drosophila melanogaster that suppresses the production and release of Insulin. The hormone is important in adaptation to starvation conditions, and represents a mechanism by which insulin is negatively regulated.[1][2][3]
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- ^ Alfa, Ronald W.; Park, Sangbin; Skelly, Kathleen-Rose; Poffenberger, Gregory; Jain, Nimit; Gu, Xueying; Kockel, Lutz; Wang, Jing; Liu, Yinghua; Powers, Alvin C.; Kim, Seung K. (February 2015). "Suppression of Insulin Production and Secretion by a Decretin Hormone". Cell Metabolism. 21 (2): 323–333. doi:10.1016/j.cmet.2015.01.006. PMC 4349554. PMID 25651184.
- ^ "Metabolism: Limostatin—a decretin—suppresses insulin production". Nature Reviews Endocrinology. 2015-02-17. doi:10.1038/nrendo.2015.20.
- ^ Conger, Krista (7 August 2014). "Researchers discover insulin-decreasing hormone in flies, humans". Stanford Medicine News Center.