JWH-185

JWH-185
JWH-185.png
Legal status
Legal status
Identifiers
CAS Number
ChemSpider
Chemical and physical data
FormulaC25H27NO
Molar mass357.497 g·mol−1
3D model (JSmol)

JWH-185 is a synthetic cannabinoid receptor ligand from the naphthoylindole family. It is the carbonyl-reduced derivative of related compound JWH-081. The binding affinity of JWH-185 for the CB1 receptor is reported as Ki = 17 ± 3 nM.[1]

In the United States, all CB1 receptor agonists of the 3-(1-naphthylmethane)indole class such as JWH-185 are Schedule I Controlled Substances.[2]

See also[edit]

References[edit]

  1. ^ Huffman JW, Mabon R, Wu MJ, Lu J, Hart R, Hurst DP, Reggio PH, Wiley JL, Martin BR (2003). "3-Indolyl-1-naphthylmethanes: new cannabimimetic indoles provide evidence for aromatic stacking interactions with the CB1 cannabinoid receptor". Bioorg. Med. Chem. 11 (4): 539–549. doi:10.1016/s0968-0896(02)00451-0. PMID 12538019.
  2. ^ 21 U.S.C. § 812: Schedules of controlled substances