ICI-190,622

ICI-190,622
ICI-190,622.svg
Clinical data
ATC code
  • None
Identifiers
CAS Number
PubChem CID
ChemSpider
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC15H17N5O
Molar mass283.328 g/mol g·mol−1
3D model (JSmol)
 ☒N☑Y (what is this?)  (verify)

ICI-190,622 is an anxiolytic drug used in scientific research. It is a pyrazolopyridine derivative, related to other anxiolytic compounds such as tracazolate, and more distantly to zaleplon. It has similar effects to benzodiazepine drugs, but is structurally distinct and so is classed as a nonbenzodiazepine anxiolytic.[1][2]

See also[edit]

References[edit]

  1. ^ Patel JB, Meiners BA, Salama AI, Malick JB, U'Prichard DC, Giles RE, Goldberg ME, Bare TM (April 1988). "Preclinical studies with pyrazolopyridine non-benzodiazepine anxiolytics: ICI 190,622". Pharmacology Biochemistry and Behavior. 29 (4): 775–9. doi:10.1016/0091-3057(88)90205-5. PMID 2901116.
  2. ^ Bare TM, McLaren CD, Campbell JB, Firor JW, Resch JF, Walters CP, Salama AI, Meiners BA, Patel JB (December 1989). "Synthesis and structure-activity relationships of a series of anxioselective pyrazolopyridine ester and amide anxiolytic agents". Journal of Medicinal Chemistry. 32 (12): 2561–73. doi:10.1021/jm00132a011. PMID 2573731.