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Cross-linked_DNA_by_nitrogen_mustard.png ‎(682 × 544 pixels, file size: 19 KB, MIME type: image/png)

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English: Two DNA bases that are cross-linked by a nitrogen mustard. Different nitrogen mustards will have different chemical groups (R). The nitrogen mustards most commonly alkylate the N7 nitrogen of guanine (as shown here) but other atoms can be alkylated.[1]
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Author Simon Caulton
  1. ↑ Siddik ZH (2005) Mechanisms of Action of Cancer Chemotherapeutic Agents: DNA-Interactive Alkylating Agents and Antitumour Platinum-Based Drugs, John Wiley & Sons, Ltd

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current10:46, 14 August 2013Thumbnail for version as of 10:46, 14 August 2013682 × 544 (19 KB)SimoncaultonUser created page with UploadWizard
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