| Crypthecodinium cohnii | |
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| Species: | C. cohnii
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| Crypthecodinium cohnii (Seligo, 1886) Chatton in Grassé, 1952 [1]
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Crypthecodinium cohnii is a species of dinoflagellate microalgae.[1] It is used industrially in the production of docosahexaenoic acid.[2] Crypthecodinium cohnii is a heterotrophic non-photosynthetic Microalgae. C. cohnii can acclimate a higher docosahexaenoic acid to polyunsaturated fatty acids ratio,[3] however current studies are trying to increase the volume of DHA production by creating mutant strains. Studies have shown that an increase in the supply of Dissolved Oxygen results in an increased production of DHA.[4] In addition to oxygen concentration, C. cohnii is known to react to a change in salinity by changing their growth rate.[5] C. cohnii's growth is highly dependent on their microbiome or environment. Most of the DHA in the Microalgae is found in the phospholipid, phosphatidylcholine.[3] C. cohnii cultures require an organic carbon source to allow for accumulation of DHA. C. cohnii has been shown to accumulate other fatty acids and starch, especially due to nutrient limitation. C. cohnii showed the greatest accumulation of lipids when grown in a pH auxostat culture.[6]
References[edit]
- ^ a b "Crypthecodinium cohnii (Seligo, 1886) Chatton in Grassé, 1952". WoRMS. World Register of Marine Species. 2010. Retrieved April 30, 2012.
- ^ Martek Biosciences Corporation (April 5, 2007). "History of Martek". Archived from the original on February 5, 2007. Retrieved March 10, 2007.
- ^ a b Jiang, Yue; Chen, Feng; Liang, Shi-Zhong (September 1999). "Production potential of docosahexaenoic acid by the heterotrophic marine dinoflagellate Crypthecodinium cohnii". Process Biochemistry. 34 (6–7): 633–637. doi:10.1016/s0032-9592(98)00134-4. ISSN 1359-5113.
- ^ Diao, Jinjin; Li, Xingrui; Pei, Guangsheng; Liu, Liangsen; Chen, Lei (May 2018). "Comparative metabolomic analysis of Crypthecodinium cohnii in response to different dissolved oxygen levels during docosahexaenoic acid fermentation". Biochemical and Biophysical Research Communications. 499 (4): 941–947. doi:10.1016/j.bbrc.2018.04.024. ISSN 0006-291X. PMID 29626468.
- ^ Jiang, Y; Chen, F (1999-12-01). "Effects of salinity on cell growth and docosahexaenoic acid content of the heterotrophic marine microalga Crypthecodinium cohnii". Journal of Industrial Microbiology and Biotechnology. 23 (6): 508–513. doi:10.1038/sj.jim.2900759. ISSN 1367-5435. S2CID 2195505.
- ^ Pleissner, Daniel; Eriksen, Niels T. (2012-03-02). "Effects of phosphorous [sic], nitrogen, and carbon limitation on biomass composition in batch and continuous flow cultures of the heterotrophic dinoflagellate Crypthecodinium cohnii". Biotechnology and Bioengineering. 109 (8): 2005–2016. doi:10.1002/bit.24470. ISSN 0006-3592. PMID 22354618.