Climazolam

Climazolam
Climazolam.svg
Clinical data
Trade names Climasol
AHFS/Drugs.com International Drug Names
ATCvet code
Legal status
Legal status
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
Formula C18H13Cl2N3
Molar mass 342.222 g/mol g·mol−1
3D model (JSmol)

Climazolam[1] (Ro21-3982) was introduced under licence as a veterinary medicine by the Swiss Pharmaceutical company Gräub under the tradename Climasol.[2] Climazolam is a benzodiazepine, specifically an imidazobenzodiazepine derivative developed by Hoffman-LaRoche. It is similar in structure to midazolam and diclazepam and is used in veterinary medicine for anesthetizing animals.[3][4]

References[edit]

  1. ^ US 4280957 – Imidazodiazepines and processes therefor
  2. ^ https://www.drugs.com/international/climazolam.html
  3. ^ Ganter M, Kanngiesser M (Aug 1991). “Effect of ketamine and its combinations with xylazine and climazolam on the circulation and respiration in swine”. Zentralbl Veterinarmed A (in German). 38 (7): 501–509. PMID 1950241.
  4. ^ Bettschart-Wolfensberger R, Taylor PM, Sear JW, Bloomfield MR, Rentsch K, Dawling S (Oct 1996). “Physiologic effects of anesthesia induced and maintained by intravenous administration of a climazolam-ketamine combination in ponies premedicated with acepromazine and xylazine”. American Journal of Veterinary Research. 57 (10): 1472–1477. PMID 8896687.