THC Science

CLCA4
Identifiers
Aliases	CLCA4, CaCC, CaCC2, chloride channel accessory 4
External IDs	OMIM: 616857 MGI: 2139744 HomoloGene: 40808 GeneCards: CLCA4
Gene location (Human)
Chr.	Chromosome 1 (human)
End	86,580,754 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	144,680,806 bp
RNA expression pattern
	Top expressed in
	Top expressed in
	More reference expression data
	n/a
Gene ontology
Molecular function
Cellular component
Biological process
	Sources:Amigo / QuickGO
Orthologs
	22802
	99663
	ENSG00000016602
	ENSMUSG00000068547
	Q14CN2
	Q6Q473
	NM_012128
	NM_207208
	NP_036260
	NP_997091
	Wikidata
View/Edit Human	View/Edit Mouse

Chloride channel accessory 4, also known as CLCA4, is a protein which in humans CLCA4 gene. The protein encoded by this gene is a chloride channel.^[5] Protein structure prediction methods suggest the N-terminal region of CLCA4 protein is a zinc metalloprotease, and the protein is not an ion channel per se.^[6]

References[edit]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000016602 - Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000068547 - Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Agnel M, Vermat T, Culouscou JM (July 1999). "Identification of three novel members of the calcium-dependent chloride channel (CaCC) family predominantly expressed in the digestive tract and trachea". FEBS Lett. 455 (3): 295–301. doi:10.1016/S0014-5793(99)00891-1. PMID 10437792. S2CID 82094058.
^ Pawłowski K, Lepistö M, Meinander N, et al. (2006). "Novel conserved hydrolase domain in the CLCA family of alleged calcium-activated chloride channels". Proteins. 63 (3): 424–39. doi:10.1002/prot.20887. PMID 16470849. S2CID 40041491.

External links[edit]

CLCA3+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
Human CLCA4 genome location and CLCA4 gene details page in the UCSC Genome Browser.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000016602 - Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000068547 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10437792-5] Agnel M, Vermat T, Culouscou JM (July 1999). "Identification of three novel members of the calcium-dependent chloride channel (CaCC) family predominantly expressed in the digestive tract and trachea". FEBS Lett. 455 (3): 295–301. doi:10.1016/S0014-5793(99)00891-1. PMID 10437792. S2CID 82094058.

[pmid16470849-6] Pawłowski K, Lepistö M, Meinander N, et al. (2006). "Novel conserved hydrolase domain in the CLCA family of alleged calcium-activated chloride channels". Proteins. 63 (3): 424–39. doi:10.1002/prot.20887. PMID 16470849. S2CID 40041491.

[1]

[2]

[3]

[4]

[5]

[6]

THC Science

Bringing Science to the Cannabis Conversation!

Cannabis Sativa

See also[edit]

References[edit]

Further reading[edit]

External links[edit]

Leave a Reply