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CACNG4
Identifiers
Aliases	CACNG4, calcium voltage-gated channel auxiliary subunit gamma 4
External IDs	OMIM: 606404 MGI: 1859167 HomoloGene: 8674 GeneCards: CACNG4
Gene location (Human)
Chr.	Chromosome 17 (human)
End	67,033,398 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	107,685,383 bp
RNA expression pattern
	Top expressed in
	Top expressed in
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function
Cellular component
Biological process
	Sources:Amigo / QuickGO
Orthologs
	27092
	54377
	ENSG00000075461
	ENSMUSG00000020723
	Q9UBN1
	Q9JJV4
	NM_014405
	NM_019431
	NP_055220
	NP_062304
	Wikidata
View/Edit Human	View/Edit Mouse

Voltage-dependent calcium channel gamma-4 subunit is a protein that in humans is encoded by the CACNG4 gene.^[5]^[6]

L-type calcium channels are composed of five subunits. The protein encoded by this gene represents one of these subunits, gamma, and is one of several gamma subunit proteins. It is an integral membrane protein that is thought to stabilize the calcium channel in an inactive (closed) state. This gene is a member of the neuronal calcium channel gamma subunit gene subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two similar gamma subunit-encoding genes.^[6]

References[edit]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000075461 - Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000020723 - Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Burgess DL, Davis CF, Gefrides LA, Noebels JL (Jan 2000). "Identification of Three Novel Ca2+ Channel γ Subunit Genes Reveals Molecular Diversification by Tandem and Chromosome Duplication". Genome Res. 9 (12): 1204–13. doi:10.1101/gr.9.12.1204. PMC 311002. PMID 10613843.
^ ^a ^b "Entrez Gene: CACNG4 calcium channel, voltage-dependent, gamma subunit 4".

External links[edit]

CACNG4+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
Human CACNG4 genome location and CACNG4 gene details page in the UCSC Genome Browser.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000075461 - Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000020723 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10613843-5] Burgess DL, Davis CF, Gefrides LA, Noebels JL (Jan 2000). "Identification of Three Novel Ca2+ Channel γ Subunit Genes Reveals Molecular Diversification by Tandem and Chromosome Duplication". Genome Res. 9 (12): 1204–13. doi:10.1101/gr.9.12.1204. PMC 311002. PMID 10613843.

[entrez-6] "Entrez Gene: CACNG4 calcium channel, voltage-dependent, gamma subunit 4".

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