|Chemical and physical data|
|Molar mass||374.45 g/mol g·mol−1|
|3D model (JSmol)|
5F-NNE1 (also known as 5F-NNEI and 5F-MN-24) is an indole-based synthetic cannabinoid that is presumed to be a potent agonist of the CB1 receptor and has been sold online as a designer drug. Given the known metabolic liberation (and presence as an impurity) of amantadine in the related compound APINACA, it is suspected that metabolic hydrolysis of the amide group of 5F-NNE1 may release 1-naphthylamine, a known carcinogen.
Sweden’s public health agency suggested classifying 5F-NNE1 as hazardous substance on November 10, 2014.
- “5F-NNEI”. Southern Association of Forensic Scientists. Retrieved 24 July 2015.
- Ariane Wohlfarth; Marisol S. Castaneto; Mingshe Zhu; Shaokun Pang; Karl B. Scheidweiler; Robert Kronstrand; Marilyn A. Huestis (May 2015). “Pentylindole/Pentylindazole Synthetic Cannabinoids and Their 5-Fluoro Analogs Produce Different Primary Metabolites: Metabolite Profiling for AB-PINACA and 5F-AB-PINACA”. The AAPS Journal. 17 (3): 660–677. doi:10.1208/s12248-015-9721-0. PMC 4406957. PMID 25721194.
- “Cannabinoider föreslås bli klassade som hälsofarlig vara”. Folkhälsomyndigheten. Retrieved 24 July 2015.