|CompTox Dashboard (EPA)|
|Chemical and physical data|
|Molar mass||291.386 g/mol g·mol−1|
|3D model (JSmol)|
JWH-030 is a research chemical which is a cannabinoid receptor agonist. It has analgesic effects and is used in scientific research. It is a partial agonist at CB1 receptors, with a Ki of 87nM, making it roughly half the potency of THC. It was discovered and named after Dr. John W. Huffman.
- Lainton JAH, Huffman JW, Martin BR,
Compton DR. Tetrahedron Letters. 1995; 36:1401.
- Pertwee RG, Griffin, G, Lainton JAH, Huffman JW. European Journal of Pharmacology. 1995; 284:241.
- Griffin, G.; Atkinson, P. J.; Showalter, V. M.; Martin, B. R.; Abood, M. E. (1998). “Evaluation of cannabinoid receptor agonists and antagonists using the guanosine-5′-O-(3-35Sthio)-triphosphate binding assay in rat cerebellar membranes”. The Journal of Pharmacology and Experimental Therapeutics. 285 (2): 553–560. PMID 9580597.