Hyakutake may refer to:

Astronomy[edit]

• Comet Hyakutake, a comet discovered in 1996

People[edit]

• Gengo Hyakutake (1882–1976), Imperial Japanese Navy admiral
• Harukichi Hyakutake (1888–1947), Imperial Japanese Army general
• Saburō Hyakutake (1872–1963), Imperial Japanese Navy admiral
• Tetsugo Hyakutake (b. 1975), Japanese artist and photographer
• Yoshinari Hyakutake,(b. 1977), Japanese football player
• Yuji Hyakutake (1950–2002), Japanese astronomer