Cannabis Ruderalis

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α-Methylhistamine
Skeletal formula of a minor tautomer of alpha-methylhistamine
Names
IUPAC name
1-(3H-Imidazol-4-yl)propan-2-amine
Systematic IUPAC name
1-(1H-Imidazol-4-yl)propan-2-amine[1]
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
MeSH Alpha-methylhistamine
  • InChI=1S/C6H11N3/c1-5(7)2-6-3-8-4-9-6/h3-5H,2,7H2,1H3,(H,8,9) checkY
    Key: XNQIOISZPFVUFG-UHFFFAOYSA-N checkY
  • InChI=1/C6H11N3/c1-5(7)2-6-3-8-4-9-6/h3-5H,2,7H2,1H3,(H,8,9)
    Key: XNQIOISZPFVUFG-UHFFFAOYAW
  • CC(N)CC1=CNC=N1
Properties
C6H11N3
Molar mass 125.175 g·mol−1
log P -0.346
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)

α-Methylhistamine is a histamine agonist selective for the receptor subtype H3. It causes lowering of blood pressure and a decrease of heart rate in animal models.[2]

References[edit]

  1. ^ "Chemical Entities of Biological Interest (ChEBI)".
  2. ^ McLeod, RL; Gertner, SB; Hey, JA (1993). "Production by R-alpha-methylhistamine of a histamine H3 receptor-mediated decrease in basal vascular resistance in guinea-pigs". Br J Pharmacol. 110 (2): 553–558. doi:10.1111/j.1476-5381.1993.tb13846.x. PMC 2175947. PMID 7902173.


source: https://en.wikipedia.org/wiki/Alpha-Methylhistamine

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