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RXFP3
Identifiers
Aliases	RXFP3, GPCR135, RLN3R1, RXFPR3, SALPR, Relaxin/insulin-like family peptide receptor 3, relaxin/insulin like family peptide receptor 3, relaxin family peptide receptor 3
External IDs	OMIM: 609445 MGI: 2441827 HomoloGene: 9568 GeneCards: RXFP3
Gene location (Human)
Chr.	Chromosome 5 (human)
End	33,938,918 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	11,038,077 bp
RNA expression pattern
	Top expressed in
	Top expressed in
	More reference expression data
	More reference expression data
Gene ontology
Molecular function
Cellular component
Biological process
	Sources:Amigo / QuickGO
Orthologs
	51289
	239336
	ENSG00000182631; ENSG00000277069
	ENSMUSG00000060735
	Q9NSD7
	Q8BGE9
	NM_016568
	NM_178717
	NP_057652
	NP_848832
	Wikidata
View/Edit Human	View/Edit Mouse

Relaxin/insulin-like family peptide receptor 3, also known as RXFP3, is a human G-protein coupled receptor.^[5]

References[edit]

^ ^a ^b ^c ENSG00000277069 GRCh38: Ensembl release 89: ENSG00000182631, ENSG00000277069 - Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000060735 - Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: RXFP3 relaxin/insulin-like family peptide receptor 3".

Further reading[edit]

Bathgate RA, Ivell R, Sanborn BM, et al. (2005). "Receptors for relaxin family peptides". Ann. N. Y. Acad. Sci. 1041 (1): 61–76. Bibcode:2005NYASA1041...61B. doi:10.1196/annals.1282.010. PMID 15956688. S2CID 1185573.
Bathgate RA, Ivell R, Sanborn BM, et al. (2006). "International Union of Pharmacology LVII: recommendations for the nomenclature of receptors for relaxin family peptides". Pharmacol. Rev. 58 (1): 7–31. doi:10.1124/pr.58.1.9. PMID 16507880. S2CID 7466039.
Matsumoto M, Kamohara M, Sugimoto T, et al. (2000). "The novel G-protein coupled receptor SALPR shares sequence similarity with somatostatin and angiotensin receptors". Gene. 248 (1–2): 183–9. doi:10.1016/S0378-1119(00)00123-2. PMID 10806363.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Liu C, Eriste E, Sutton S, et al. (2004). "Identification of relaxin-3/INSL7 as an endogenous ligand for the orphan G-protein-coupled receptor GPCR135". J. Biol. Chem. 278 (50): 50754–64. doi:10.1074/jbc.M308995200. PMID 14522968.
Liu C, Chen J, Kuei C, et al. (2005). "Relaxin-3/insulin-like peptide 5 chimeric peptide, a selective ligand for G protein-coupled receptor (GPCR)135 and GPCR142 over leucine-rich repeat-containing G protein-coupled receptor 7". Mol. Pharmacol. 67 (1): 231–40. doi:10.1124/mol.104.006700. PMID 15465925. S2CID 25164369.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Van der Westhuizen ET, Sexton PM, Bathgate RA, Summers RJ (2005). "Responses of GPCR135 to human gene 3 (H3) relaxin in CHO-K1 cells determined by microphysiometry". Ann. N. Y. Acad. Sci. 1041 (1): 332–7. Bibcode:2005NYASA1041..332V. doi:10.1196/annals.1282.053. PMID 15956730. S2CID 2468316.

External links[edit]

"Relaxin Family Peptide Receptors: RXFP3". IUPHAR Database of Receptors and Ion Channels. International Union of Basic and Clinical Pharmacology. Archived from the original on 2016-03-03. Retrieved 2008-12-09.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

[refGRCh38Ensembl-1] ENSG00000277069 GRCh38: Ensembl release 89: ENSG00000182631, ENSG00000277069 - Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000060735 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: RXFP3 relaxin/insulin-like family peptide receptor 3".

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