Pyridinylpiperazine
Names
Preferred IUPAC name
1-(Pyridin-2-yl)piperazine
Identifiers
ChEMBL
ChemSpider
ECHA InfoCard
100.047.458
EC Number
UNII
InChI=1S/C9H13N3/c1-2-4-11-9(3-1)12-7-5-10-6-8-12/h1-4,10H,5-8H2
Y Key: GZRKXKUVVPSREJ-UHFFFAOYSA-N
Y InChI=1S/C9H13N3/c1-2-4-11-9(3-1)12-7-5-10-6-8-12/h1-4,10H,5-8H2
InChI=1S/C9H13N3/c1-2-4-11-9(3-1)12-7-5-10-6-8-12/h1-4,10H,5-8H2
Key: GZRKXKUVVPSREJ-UHFFFAOYSA-N
Properties
C9 H13 N3
Molar mass
163.22 g/mol
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
Chemical compound
1-(2-Pyridinyl)piperazine is a chemical compound and piperazine derivative . Some derivatives of this substance are known to act as potent and selective α2 -adrenergic receptor antagonists , such as 1-(3-fluoro-2-pyridinyl)piperazine.[1]
A few pyridinylpiperazine derivatives are drugs , including:
See also [ edit ]
References [ edit ]
^ Saari WS, Halczenko W, King SW, et al. (December 1983). "Pyridinylpiperazines, a new class of selective alpha 2-adrenoceptor antagonists". Journal of Medicinal Chemistry . 26 (12): 1696–701. doi :10.1021/jm00366a007 . PMID 6139479 .
Simple piperazines(no additional rings) Phenylpiperazines
2C-B-PP
3,4-CFP
Acaprazine
Antrafenine
Aripiprazole
Batoprazine
Bifeprunox
BRL-15,572
Ciprofloxacin
CSP-2503
Dapiprazole
DCPP
DMPP
Diphenylpiperazine
Dropropizine
EGIS-12,233
Elopiprazole
Eltoprazine
Enpiprazole
Ensaculin
Etoperidone
Flesinoxan
Fluanisone
Flibanserin
Fluprazine
Itraconazole
Ketoconazole
Levodropropizine
Lorpiprazole
mCPP
Mefway
MeOPP
Mepiprazole
Naftopidil
Naluzotan
Naphthylpiperazine
Nefazodone
Niaprazine
Oxypertine
Pardoprunox
pCPP
pFPP
Posaconazole
S-14,506
S-14,671
S-15,535
SB-258,585
SB-271,046
SB-357,134
SB-399,885
Sonepiprazole
TFMPP
Tolpiprazole
Trazodone
Urapidil
Vesnarinone
Vilazodone
Vortioxetine
WAY-100,135
WAY-100,635
Benzylpiperazines Diphenylalkylpiperazines (benzhydrylalkylpiperazines) Pyrimidinylpiperazines Pyridinylpiperazines Benzo(iso)thiazolyl piperazines Tricyclics (piperazine attached via side chain) Others/Uncategorized