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This article is about a non-clinically used antiandrogen compound. For the pharmaceutical drug, see osaterone acetate.
Osaterone
Clinical data
Other namesTZP-5258; Gestoxarone; 2-Oxachloromadinone; 17α-Hydroxy-6-chloro-2-oxa-6-dehydroprogesterone; 17α-Hydroxy-6-chloro-2-oxapregna-4,6-diene-3,20-dione
Identifiers
  • (1R,3aS,3bR,9aR,9bS,11aS)-1-acetyl-5-chloro-1-hydroxy-9a,11a-dimethyl-2,3,3a,3b,9,9b,10,11-octahydroindeno[4,5-h]isochromen-7-one
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC20H25ClO4
Molar mass364.87 g·mol−1
3D model (JSmol)
  • CC(=O)[C@]1(CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2C=C(C4=CC(=O)OC[C@]34C)Cl)C)O
  • InChI=1S/C20H25ClO4/c1-11(22)20(24)7-5-14-12-8-16(21)15-9-17(23)25-10-18(15,2)13(12)4-6-19(14,20)3/h8-9,12-14,24H,4-7,10H2,1-3H3/t12-,13+,14+,18-,19+,20+/m1/s1
  • Key:ZLLOIFNEEWYATC-XMUHMHRVSA-N

Osaterone (developmental code name TZP-5258), also known as 17α-hydroxy-6-chloro-2-oxa-6-dehydroprogesterone, as well as 2-oxachloromadinone, is a steroidal antiandrogen and progestin that was never marketed.[1][2] The C17α acetate ester of osaterone, osaterone acetate, in contrast, has been marketed.[1][2]

See also[edit]

References[edit]

  1. ^ a b Index Nominum: International Drug Directory. MedPharm. 2011. ISBN 978-3-8047-5053-1.
  2. ^ a b Milne GW (8 May 2018). Drugs: Synonyms and Properties: Synonyms and Properties. Taylor & Francis. pp. 969–. ISBN 978-1-351-78989-9.



source: https://en.wikipedia.org/wiki/Osaterone

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