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English: Figure 8. Cannabinoid receptor activation reduces invasiveness. A significant reduction in the number of invaded cells was seen after treatment with WIN (p = 0.0081; A). A near-complete reversal of the reduced invasiveness was seen when the cells were pre-incubated with AM251 or a combination of AM251 and AM630 (A). This was not found with AM630 alone (A). WIN induced a significant decrease in MMP-2 levels (p = 0.026; B) which was partially reversible by a combination of AM251 and AM630 (B). Actin cytoskeleton staining with phalloidin demonstrated that control PSC showed the normal cellular structure (C&D) but that WIN induced a more round and smaller PSC phenotype (E&F). Original magnification: x 40 (C&E), x 80 (D&F). Nuclear stain: DAPI. White bars: control; black bars: WIN55,212-2±AM251/AM630. Data are shown as mean±SEM. Русский: Агонист каннабиноидных рецепторов снижает характеристики воспаления в панкреатических звездчатых клетках. |
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This is a retouched picture, which means that it has been digitally altered from its original version. Modifications: crop. The original can be viewed here: Cannabioid agonist WIN acting on pancreatic stellate cell.png:  . Modifications made by CopperKettle.
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This image is a derivative work of the following images:
- File:Cannabioid_agonist_WIN_acting_on_pancreatic_stellate_cell.png licensed with Cc-by-2.5
- 2009-08-28T18:30:49Z CopperKettle 2000x2516 (1943013 Bytes) downsize
- 2009-08-28T18:28:09Z CopperKettle 4134x5201 (2913653 Bytes) {{Information |Description={{en|1=Figure 5. AM251 induces changes in PSC phenotype. (A) Invasion assays demonstrated a trend toward increased invasiveness induced by AM251. (B) MMP-2 levels were unchanged by antagonist treat
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 05:38, 29 August 2009 | | 1,001 × 1,570 (769 KB) | CopperKettle | {{Information |Description={{en|1=Figure 8. Cannabinoid receptor activation reduces invasiveness. A significant reduction in the number of invaded cells was seen after treatment with WIN (p = 0.0081; A). A near-complete reversal of the reduced invasivene |
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