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| Formula | C11H14N2O |
| Molar mass | 190.246 g·mol−1 |
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Norpsilocin (4-HO-NMT) is a tryptamine alkaloid recently discovered in 2017 in the psychedelic mushroom Psilocybe cubensis.[1][2] It is hypothesized to be a dephosphorylated metabolite of baeocystin.[2] Norpsilocin was found to be a near full agonist of the 5-HT2A receptor. It is also more potent than psilocin.[3][4]
See also[edit]
References[edit]
- ^ Lenz C, Wick J, Hoffmeister D (October 2017). "Identification of ω-N-Methyl-4-hydroxytryptamine (Norpsilocin) as a Psilocybe Natural Product". Journal of Natural Products. 80 (10): 2835–2838. doi:10.1021/acs.jnatprod.7b00407. PMID 28929753.
- ^ a b "Two New Crystalline Forms of Norpsilocin".
- ^ "Study Finds Norpsilocin is More Potent Than Psilocin at 5-HT2A".
- ^ Sherwood AM, Halberstadt AL, Klein AK, McCorvy JD, Kaylo KW, Kargbo RB, Meisenheimer P (February 2020). "Synthesis and Biological Evaluation of Tryptamines Found in Hallucinogenic Mushrooms: Norbaeocystin, Baeocystin, Norpsilocin, and Aeruginascin". Journal of Natural Products. 83 (2): 461–467. doi:10.1021/acs.jnatprod.9b01061. PMID 32077284.